Cyno CTR COS7
CBP71648
詢 價(jià)
索取protocol
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
| I. Background | |
| Cyno CTR（食蟹猴降鈣素受體，基因 CALCR）? 是與人高度同源（>97%）的 B 類七次跨膜 GPCR，主要表達(dá)于破骨細(xì)胞、甲狀腺 C 細(xì)胞及腎小管，結(jié)合降鈣素（Calcitonin）激活 Gs/Gq→cAMP/Ca²? 通路，抑制骨吸收、促進(jìn)尿鈣排泄以維持鈣磷穩(wěn)態(tài)。 | |
| II. Description | |
| Cyno CTR COS7 細(xì)胞藥靶模型很好的模擬了體內(nèi) CTR 的信號轉(zhuǎn)導(dǎo)過程。 | |
| III. Introduction | |
| Host Cell: |
COS7 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: |
DMEM+10%FBS+2μg/ml Puromycin
|
| Mycoplasma Status: | Negative |
| Storage: | Liquid nitrogen immediately upon delivery |
| Application(s): |
Functional assay for Cyno CTR |
| Transducer: | Gs |
| IV. Representative Data | |
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